Resource Type

Journal Article 381

Year

2023 30

2022 26

2021 46

2020 43

2019 24

2018 25

2017 21

2016 17

2015 22

2014 20

2013 14

2012 8

2011 5

2010 21

2009 16

2008 8

2007 12

2005 2

2004 1

2003 1

open ︾

Keywords

COVID-19 9

Coronavirus disease 2019 8

China 6

epidemiology 6

inflammation 6

Alzheimer’s disease 5

Artificial intelligence 4

Deep learning 4

chronic kidney disease 4

coronavirus disease 2019 (COVID-19) 4

Coronavirus disease 3

human immunodeficiency virus (HIV) 3

traditional Chinese medicine 3

β 2

-catenin 2

2019-nCoV 2

Artificial intelligence 2.0 2

Bacteria 2

Bioaccessibility 2

open ︾

Search scope:

排序： Display mode:

Zooming in and out of ferroptosis in human disease

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 173-206 doi: 10.1007/s11684-023-0992-z

Abstract: ferroptosis and its regulatory pathways could provide additional strategies for the management of these diseasereview, we summarize the progress in the research into ferroptosis and its regulatory mechanisms in humandisease, while providing evidence in support of ferroptosis as a target for the treatment of these diseasesWe also discuss our perspectives on the future directions in the targeting of ferroptosis in human disease

Keywords： ferroptosis     human disease     iron metabolism     lipid peroxidation     antioxidation    

HTML PDF Collect

Progress on the research and development of human enterovirus 71 (EV71) vaccines

Zhenglun Liang, Qunying Mao, Fan Gao, Junzhi Wang

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 111-121 doi: 10.1007/s11684-012-0237-z

Abstract:

Enterovirus 71 (EV71) infections, which can cause severe complications, have become one of the serious public health issues in the Western Pacific region and China. To date, a number of pharmaceutical companies and institutes have initiated the research and development of EV71 vaccines as a countermeasure. As is the case with innovative vaccine development, there are several critical bottlenecks in EV71 vaccine development that must be overcome before the clinical trials, including the selection of vaccine strain, standardization of the procedure for quantifying neutralizing antibody (NTAb) and antigen, establishment and application of a reference standard and biological standards, development of animal models for the evaluation of protective efficacy, and identification of the target patient population. To tackle these technical obstacles, researchers in Mainland of China have conducted a series of studies concerning the screening of vaccine strains and the establishment of criteria, biological standards and detection methods, thereby advancing EV71 vaccine development. This review summarizes recent worldwide progress on the quality control and evaluation of EV71 vaccines.

Keywords： enterovirus 71 (EV71)     hand     foot     and mouth disease (HFMD)     vaccine    

HTML PDF Collect

Influence of Probiotic Fermented Fruit and Vegetables on Human Health and the Related Industrial Development Review

Qianqian Guan, Tao Xiong, Mingyong Xie

Engineering 2021, Volume 7, Issue 2,   Pages 212-218 doi: 10.1016/j.eng.2020.03.018

Abstract: Fermentation technology provides a new approach to the study of the effect of probiotics on human health

Keywords： Probiotic     Fermented fruit and vegetables     Human health     Chronic disease prevention    

HTML PDF Collect

The Human Microbiota in Health and Disease

Baohong Wang, Mingfei Yao, Longxian Lv, Zongxin Ling, Lanjuan Li

Engineering 2017, Volume 3, Issue 1,   Pages 71-82 doi: 10.1016/J.ENG.2017.01.008

Abstract:

Trillions of microbes have evolved with and continue to live on and within human beings.environmental factors can affect intestinal microbial imbalance, which has a close relationship with humanhealth and disease.Current research on the human microbiota has become much more sophisticated and more comprehensive.mechanisms, which could pave the way to an understanding of the role of gut microbiota in health and disease

Keywords： Microbiome     Health     Infectious disease     Liver diseases     Gastrointestinal malignancy     Metabolic disorder     Microbiota    

HTML PDF Collect

Study on Family Collection, Gene Mapping, Gene Identification and Gene Function of Human Genetic Diseases

Xia Jiahui

Strategic Study of CAE 2000, Volume 2, Issue 11,   Pages 1-11

Abstract: this paper, the study on family collection, gene mapping, gene identification and gene function of humanchromosome t (1; 3) (q44; p11) associated with nasopharyngeal cancer was found in 1975 at first, and humanIn 1998, GJB3, a human genetic neurological deafness gene, was identified using a novel strategy of “Gene Family-Candidate Disease Gene Cloning”，and the paper was published in Nature Genetics

Keywords： genetic disease     gene mapping and cloning     gene familiy-candidate disease gene cloning     genome wide scan    

HTML PDF Collect

Challenges of human–machine collaboration in risky decision-making

Frontiers of Engineering Management 2022, Volume 9, Issue 1,   Pages 89-103 doi: 10.1007/s42524-021-0182-0

Abstract: The purpose of this paper is to delineate the research challenges of human–machine collaboration in riskyTechnological advances in machine intelligence have enabled a growing number of applications in human–machineWe first summarize features of risky decision-making and possible biases of human decision-makers thereinAfterward, we review the literature on human–machine collaboration in a general decision context, fromthe perspectives of human–machine organization, relationship, and collaboration.

Keywords： human–machine collaboration     risky decision-making     human–machine team and interaction     task allocation     human–machine relationship    

HTML PDF Collect

et’s disease in a Chinese population

Shengping Hou, Aize Kijlstra, Peizeng Yang

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 354-359 doi: 10.1007/s11684-012-0234-2

Abstract: et’s disease is defined as a multisystemic inflammatory disease.et’s disease. To explore the genetic factors for Beh?et’s disease, our group investigated the association of Beh?et’s disease with multiple immune response genes and has identified multiple Beh?et’s disease-related immunoregulatory pathways in the Chinese Han population.

Keywords： et’s disease     SNPs     immune gene     genetic study    

HTML PDF Collect

Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 425-432 doi: 10.1007/s11684-013-0295-x

Abstract:

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality

Keywords： chronic obstructive pulmonary disease     heterogeneity     phenotype     genotype     prediction    

HTML PDF Collect

Tackling global electricity shortage through human power: Technical opportunities from direct or indirectutilizations of the pervasive and green human energy

Dan DAI, Jing LIU

Frontiers in Energy 2012, Volume 6, Issue 3,   Pages 210-226 doi: 10.1007/s11708-012-0200-3

Abstract: With the energy and environmental problems becoming increasingly serious, human power, as a pervasiveIn this paper, the most basic features of human power are presented.The currently available human power harvesting theories and devices are briefly reviewed and compared, which are termed as human-powered grid (HPG), human-powered charger (HPC) and human-powered storageconverts human power into electricity.

Keywords： human energy harvesting     human-powered transportation     human-powered home appliances     human-powered grid(HPG)     human-powered charger (HPC)     human-powered storage (HPS)     biofuel    

HTML PDF Collect

Acupuncture for the management of dry eye disease

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 975-983 doi: 10.1007/s11684-022-0923-4

Abstract: The effectiveness of using acupuncture for dry eye disease (DED) is controversial.outcomes of interests were (1) to evaluate the efficacy of acupuncture in improving the ocular surface disease

Keywords： dry eye disease     xerophthalmus     acupuncture    

HTML PDF Collect

Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Frontiers of Engineering Management 2015, Volume 2, Issue 1,   Pages 2-12 doi: 10.15302/J-FEM-2015002

Abstract: the status of major chronic diseases in China, analyzing the key issues and key factors in chronic diseasethe previous projects, this paper proposes the following recommendations as strategies for chronic diseaseWork norms and requirements will then improve the performance and efficiency in chronic disease prevention

Keywords： chronic disease prevention and control     strategy and system construction    

HTML PDF Collect

Implantation of human umbilical cord mesenchymal stem cells for ischemic stroke: perspectives and challenges

Yingchen Li,Guoheng Hu,Qilai Cheng

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 20-29 doi: 10.1007/s11684-014-0371-x

Abstract: As a neuroregenerative therapy, the implantation of human umbilical cord mesenchymal stem cells (hUC-MSCs

Keywords： cellular therapy     transplantation     human umbilical cord     mesenchymal stem cells     ischemic stroke    

HTML PDF Collect

Astrocytes in depression and Alzheimer’s disease

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 829-841 doi: 10.1007/s11684-021-0875-0

Abstract: brain diseases may cause psychosocial and cognitive impairment, such as depression and Alzheimer’s diseasedisability, resulting in gradual loss of self-care ability, lower life qualities, and vast burden on humandepression and AD has shown that depression might be a prodrome of progressive degenerative neurological disease

Keywords： astrocytes     depression     Alzheimer’s disease     roles     mechanisms    

HTML PDF Collect

Minimal residual disease in solid tumors: an overview

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 649-674 doi: 10.1007/s11684-023-1018-6

Abstract: Minimal residual disease (MRD) is termed as the small numbers of remnant tumor cells in a subset of patients

Keywords： MRD     solid tumor     CTC     ctDNA    

HTML PDF Collect

Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 480-489 doi: 10.1007/s11684-017-0594-8

Abstract:

Superinfection is frequently detected among individuals infected by human immunodeficiency virus type

Keywords： human immunodeficiency virus type I     superinfection     incidence     immune response    

HTML PDF Collect

Title Author Date Type Operation

Zooming in and out of ferroptosis in human disease

Journal Article

Progress on the research and development of human enterovirus 71 (EV71) vaccines

Zhenglun Liang, Qunying Mao, Fan Gao, Junzhi Wang

Journal Article

Influence of Probiotic Fermented Fruit and Vegetables on Human Health and the Related Industrial Development

Qianqian Guan, Tao Xiong, Mingyong Xie

Journal Article

The Human Microbiota in Health and Disease

Baohong Wang, Mingfei Yao, Longxian Lv, Zongxin Ling, Lanjuan Li

Journal Article

Study on Family Collection, Gene Mapping, Gene Identification and Gene Function of Human Genetic Diseases

Xia Jiahui

Journal Article

Challenges of human–machine collaboration in risky decision-making

Journal Article

et’s disease in a Chinese population

Shengping Hou, Aize Kijlstra, Peizeng Yang

Journal Article

Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Journal Article

Tackling global electricity shortage through human power: Technical opportunities from direct or indirectutilizations of the pervasive and green human energy

Dan DAI, Jing LIU

Journal Article

Acupuncture for the management of dry eye disease

Journal Article

Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Journal Article

Implantation of human umbilical cord mesenchymal stem cells for ischemic stroke: perspectives and challenges

Yingchen Li,Guoheng Hu,Qilai Cheng

Journal Article

Astrocytes in depression and Alzheimer’s disease

Journal Article

Minimal residual disease in solid tumors: an overview

Journal Article

Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Journal Article